ALKALINE PHOSPHATASE STATUS IN THYROTOXIC INDIVIDUALS
Objectives: To investigate the effect of thyroid hormones, free tri-iodothyronine (T3) and free tetra-iodothyronine (T4),
on serum alkaline phosphatase in thyrotoxic individuals of Khyber Pakhtunkhwa.
Methods: This comparative cross sectional study had 50 thyrotoxic individuals and 50 controls. Demographic and
clinical data of the study individuals was recorded by interviewing and examining them. Blood samples were analyzed
for serum FT3, T4, and TSH concentration at RIA laboratory, Institute of Radiotherapy and Nuclear Medicine (IRNUM).
Serum ALP was determined in Hitech laboratory, Aman Hospital Peshawar respectively. The data was analyzed on
SPSS version 13.0 using student t- test.
RESULTS: There was a significant difference between the two groups regarding serum ALP with a P – value of < 0.001
Conclusion: A high concentration of ALP was found in thyrotoxic patients of Khyber Pakhtunkhwa.
Keywords: Free T3, serum ALP, thyrotoxic, freeT4, and TSH