COMPARISON OF SD ICT KIT AND ARCHITECT FOR THE SCREENING OF HEPATITIS B VIRUS

Abstract

ABSTRACT
Objective of study: To compare ICT HBsAg with Architect i1000 for the diagnosis of HBsAg.
Material & Methods: The study was carried out at RMI laboratory from healthy blood donors from 2nd May 2017 till 1st
July 2017.After taking history and excluding already known patients of any chronic illness and high risk people such
as sex workers and I/V drug abusers, 257 samples were collected for the study. The samples were then tested on both
& SD HBsAg ICT kit and architect.The result were analyzed on using SPSS version 15.0.
Results: Out of 257 donors 97.7% were males and 2.3% were females. B+ve was the blood group in the highest
frequency according to our study followed by O+ve,A+Ve&AB+ve. Architect showed that 10 donors i.e 3.9% were
positive for HBsAg.Whereas HBsAg ICT showed reactivity of 7 people that is 2.7% so, it missed three cases which is
positive in Architect. And the sensitivity came out to be 70%.
Conclusion: The sensitivity of the best available SDICT kit in Peshawar used by most of the laboratories is very less
according to our study. So, missing out a large numbers of positive hepatitis B cases. Therefore although they can be
used as a screening test. But should be confirmed by a more sensitive method as EIA or NAAT.

Authors: 
Zufishan Batool1
Nosheen Ali1
Zahra Ahmad2
Aurangzeb
Shifa Basharat1
Sidra Hamayun2
Journal Issue: 

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