CORRELATION BETWEEN BODY MASS INDEX AND FORCED EXPIRATORY VOLUME IN ONE SECOND IN PATIENTS WITH COPD
Background: Chronic obstructive pulmonary disease (COPD) is a respiratory disease that is characterized by airflow
obstruction that is persistent, progressive in nature and not fully reversible. There is increasing evidence that COPD
leads to weight loss and result in low Body Mass Index (BMI) which is poor prognostic factor in these patients. This
study was conducted to determine the correlation between Body Mass Index (BMI) and Forced Expiratory Volume in
one second (FEV1) in patients with Chronic Obstructive Pulmonary Disease.
Methods: This cross-sectional study was conducted in the Pulmonology wards/OPD’s of Khyber Teaching Hospital
Peshawar. A total of 141 cases were studied based on 0.35 correlations between BMI and FEV1, with the confidence
level of 95% and 99% power of the test. All patients having stable Chronic Obstructive Pulmonary Disease of either
gender with age more than 40 years were included. Patients diagnosed with asthma, acute exacerbation of COPD
and weight loss due to any reason were excluded. BMI and FEV1 of all patients who fulfilled the diagnostic criteria for
Chronic Obstructive Pulmonary Disease as per Pakistan Chest Society Guidelines (FEV1 <70% predicted & FEV1/
FVC ratio <70%) were recorded.
Results: Out of 141 patients, 51 % were females and 49% were males. Mean FEV1 was 44.32% ± 1.68. Twenty four
percent patients had very severe COPD (FEV1 < 30%), 41% patients had severe COPD (FEV1 ranged from 30-49%),
29% patients had moderate COPD (FEV1 ranged from 50-79%) and 6% patients had mild COPD (FEV1>80%). Mean
BMI score was 19.53 ± 4.9. Fifty one percent of the patients had BMI score < 18.5, 34% patients had BMI score 18.5–25,
and 15% patients had BMI score > 25. In our study, 51% of all the patients had a BMI of <18.5. Among these patients
with very severe, severe and moderate COPD had a low BMI`s in 85.29%, 62.06% and 17.07% of patients respectively.
No patient with mild COPD had low BMI.
Conclusion: There is positive correlation between FEV1 severity and BMI.
Key Words: COPD, body mass index (BMI), forced expiratory volume in one second (FEV1).
286 KJMS September-December, 2017, Vol. 10, No. 3