EFFECTIVENESS OF SOFOSBUVIR AND RIBAVIRIN IN CHRONIC HEPATITIS C GENOTYPE 2 AND 3 PATIENTS

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Abstract

ABSTRACT
Objective: To determine the effecctiveness of Sofosbuvir and Ribavirin in chronic hepatitis C genotype 2 and 3 patients.
Study Design: Retrospective study
Place and Duration: January 15th 2015 and November 19th 2016, DHQ hospital Swabi
Materials and Methods: A total of 150 cases of Chronic hepatitis Cwere taken who attended the hospital between
January 15th 2015 to November 19th 2016 were included in this study and their PCR done at 4 and 12 weeks for genotype
2,4 and 24 weeks for genotype 3, and 3months after the completion of treatment. It comprises of both treatment
naive (those who had not been treated previously for Hepatitis C) and treatment experienced (those who had previous
treatment failure for hepatitis C or relapse, either due to the drug intolerance, drug resistance and/or other factors).
SPSS v21 was used to analyze the data.
Results: The total number of patients was 150, number of male patients was 80 and females were 70 in both genotypes

Authors: 
Jawad Khan3
Muhammad Imranullah1
Saira Nasr Malik
Noor Ul Amin
Muhammad Daud

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