FREQUENCY OF NEWLY DIAGNOSED HEPATITIS B AND C VIRUSES IN PATIENTS WITH HUMAN IMMUNODEFICIENCY VIRUS AND THEIR COMMON LEADING FACTORS

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Abstract

 

ABSTRACT
Objective: To determine the frequency of Hepatitis B and C viruses in patients with Human immunodeficiency virus
(HIV) and their common leading factors in Khyber Pakhtun Khuwa (KPK).
Methadology: This discrive stduy was performed at Anti Retroviral Therapy (ART) center, Peshawar from 5 years from
January 2006 to June 2011. Total of 710 patients were registered/diagnosed with HIV during this period; All patients
were analyzed for the presence of Hepatitis B virus (HBV) and Hepatitis C virus (HCV) on the basis of the presence of
HBs Ag and anti-HCV markers.
Results: In patients infected with HIV, the frequency of co-infection with HBV was 9.57% (68/710), with HCV was 6.76%
(48/710) and with both HBV and HCV was 2.39% (17/710). Commonest leading factor was intravenous drug use (IVU)
53%, 66%, and 53% for HIV and HBV, HIV and HCV, HIV HBV and HCV co-infections respectively followed by blood
transfusion, heterosexual transmission, male having sex with male (MSM), vertical transmission respectively.
Conclusion: The frequency of HBV and HCV co infections is increasing in patients infected with HIV and they share
common leading factors so its essential that all the patients infected with HIV be screened for HBV and HCV co-infection
as early treatment of hepatitis can significantly decreases the morbidity and mortality.
Keywords: HIV, HBV, HCV, frequency, co-infection, IDU, blood transfusion, heterosexual transmission, MSM, vertica
Authors: 
Muhammad1 Bilal Awan
Saad Ali1
Yaseen Khan1

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