SNUFF SIPPING AS A RISK FACTOR FOR SQUAMOUS CELL CARCINOMA OF THE ORAL CAVITY
Objective: To determine the association of snuff dipping with SCC of the oral cavity.
Methodology: This case control study was conducted at department of dentistry of Ayub Teaching Hospital (ATH),
Abbottabad over a period of six months. A total of 31 cases of oral SCC, fulfilling inclusion and exclusion criteria were
selected. Tissue biopsies were submitted to the histopathology departments of Ayub Medical College, Abbottabad and
Armed Forces Institute of Pathology, Rawalpindi. Same number of controls with similar age and gender were selected
and history regarding snuff dipping was taken.
Results: Out of 31 patients of SCC, 24 were having history of chronic snuff dipping. Most of the patients were above the
age of 45 years with the mean age of 53.90 (SD+13.73) while male to female ratio was 3.1: 2. Oral SCC developed at
the site of placement of snuff in 75.5% of the patients and the most common site of SCC was lower left buccal sulcus.
Among 31 controls, only six (19.35%) people were snuff users. Oral SCC was found to be associated with the snuff
dipping having an Odds ratio of 14.28 and a P value of 0.00.
Conclusion: The snuff dippers are at a high risk of developing oral SCC as compared to non-dippers, both in males
and females. People should be educated about the serious side effect of this social habit, snuff dipping.
Key words: Snuff dipping, squamous cell carcinoma, oral cavity, buccal sulcus, tobacco, naswar.