ASSESSMENT OF THYROID PROFILE AND ITS CO-RELATION WITH DIFFERENT BLOOD GLUCOSE LEVELS

ABSTRACT
Background: This is an endocrine gland situated in the lower part of the front and side of the neck. It resembles an
H in shape. (Follicles). These are spherical sacs consist of simple epithelial cells and whose lumen contains colloid.
The wall of each follicle consists of two types of cells Follicular cells these cells reach the surface of the lumen of the
follicle. They manufacture thyroxine T4 90 % and tri-iodothyronine 10 %. Para Follicular cells (C-cells). These are cells,
which do not reach the lumen. They produce calcitonin. When the cells are inactive, they tend to be low cuboidal to
squamous type, but when actively secreting hormones, they become more columnar.
Objectives: To determine TFTs and fasting and random blood glucose and to study co-relation of hypo and hyper
thyroidism with Diabetes Mellitus.
Results: Mean age of the patients was 38.26±13.157 ranging from 13 to 75 years and mean T3 was 1.6120±0.84991
ranging from 0.50 to 3.80, mean TSH was 5.2055±13.47513 ranging from 0.10 to 88.00, mean T4 was 11.1294±5.84739,
mean blood glucose (F) was 82.01±18.504 ranging from 70 to 208 and mean (R) was 112.59±35.373 ranging from
90 to 398. Among TFTs, 121(60.5%) were normal patients and 29(14.5%) had Hypo-thyroidism and the remaining 50
(25.0%) had Hyper-thyroidism out of the total 200 patients Out of total 6 diabetic patients, 3 had normal TSH and 3 had
Hypo-thyroidism, while no patients had Hyper-thyroidism, while 194 non-diabetic patients, 118 had normal TSH, 50
had Hyper-thyroidism and 26 had Hypo-thyroidism out of total 200 patients. Out of 6 diabetic patients, 3 had normal T4
and 3 had Hypo-thyroidism, while no patients had Hyper-thyroidism, while 194 non-diabetic patients, 119 had normal
T4, 52 had Hyper-thyroidism and 23 had Hypo-thyroidism out of total 200 patients. Out of total 6 diabetic patients, 3
had normal T3 and 3 had Hypo-thyroidism, while no patients had Hyper-thyroidism, while 194 non-diabetic patients,
131 had normal T3, 47 had Hyper-thyroidism and 16 had Hypo-thyroidism out of total 200 patients.
Conclusion: There was no correlation found in our study between diabetic and thyroid patients as well. Further studies
may be conducted on the same topic increasing the sample size of the study to evaluate the correlation between the
outcomes.
Key Words: thyroid profile, Co-relation, different blood glucose levels.