ASSOCIATION OF THYROID HORMONES WITH DYSFUNCTIONAL UTERINE BLEEDING AND EFFECTS OF MENORRHAGIA IN YOUNG GIRLS OF DISTRICT PESHAWAR KHYBER PUKKTOONKHWA

ABSTRACT
Introduction: Menstrual disorders in adolescence may present diagnostic and management challenges for the gynecologist.
It is a particularly common issue for young girls. Abnormal uterine bleeding is a common problem and its
management can be complex. Thyroid hormones play a key role in the menstrual and reproductive function of women.
It is recognized universally that menstrual disturbances may accompany clinical alterations in thyroid function.
Objective: To find out the prevalence of thyroid disorder in dysfunctional uterine bleeding patients.
Method: A hospital based cross sectional study was carried out at Department of Gynecology and Obstetrics, Khyber
Teaching Hospital, Peshawar and the data was analyzed at Department of Biochemistry, Khyber Medical College Peshawar,
Khyber Pakhtunkhwa Pakistan. The study subjects were randomly selected and the data was recorded on a
predesigned and prestructured questionnaire developed for the study. Blood was analyzed for determination of serum
T3, T4, TSH respectively.
Results: Most of the dysfunctional uterine bleeding cases were in the age group of 15–24 years (74.30%) followed
by 25-35 years (25.70%) respectively. The commonest menstrual complaint was menorrhagia which was present in
hypothyroidism (26.70%) while in hyperthyroidism it was (22.0%).
Conclusions: Thyroid dysfunction is associated with menstrual disturbances. Prevalence of hypothyroidism was more
common than hyperthyroidism in subjects diagnosed with dysfunctional uterine bleeding