DETECTION OF HUMAN PAPILLOMAVIRUS 16 AND 18 DNA FROM ORAL EPITHELIAL CELLS BY THE REAL TIME PCR IN NORMAL ORAL CAVITY IN QUETTA

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Abstract

ABSTRACT
Background: Human papillomavirus (HPV) are small DNA tumor viruses that play a great part in a number of benign
and malignant proliferative diseases. The presence of the virus is often associated with the proliferation of benign and
malignant neoplasms of the oral cavity and genital area. Among the HPV linked malignancies, HPV16 is prevailed
higher than HPV18 in Oral Squamous Cell Carcinomas and in Oropharyngeal Carcinoma. The purpose of this cross
sectional study was to investigate the prevalence of high risk HPV 16 and 18, and the association with its risk factors
among Dental Patients with healthy oral mucosa

Authors: 
Abdul Samad Gichki1
Khalil Ahmed2
Mujeeb ur Rehman Baloch3

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