EFFECT OF ASPIRIN IN TURP

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Abstract

ABSTRACT
Background:Many of the patients candidates for TURP,also suffer from cardiovascular disease and are under medications
with low dose aspirin.Aspirin withdrawal may result in acute cardiovascular syndrome while its continuation may
expose patients to he risk of post-surgical excessive bleeding.There are no guidelines whether to continue aspirin or
stop it.This study aims to determine the impact of aspirin om peri-operative and post-operative blood loss.
Material and Methods:A total of 160 patients undergoing TURP were divided in two equal groups of 80.Group A
continued taking aspirin and group B stopped aspirin 10 days prior to surgery.Bleeding complications during and 10
days post-operatively were recorded .
Result:The mean age of patients in group A was 66+/-8.56 and group B 68+/-7.28.Wt of prostate resected in group
A 30gm/42mins and group B32gm/46mins.Per-operatively 8(10%) in group A and 7(8.7%) in group B had severe
heamorrhage.In 1st 48hrs 23(28.7%) in group A and 12(15%) in group B had severe heamorrhage .Re-admission in 1st
10 days was 5(6.2%) in group A and 1(1.2%) in group B.
Conclusion:Aspirin should be stopped pre-operatively for the danger of excessive post-op heamorrhage.It is safe to
do so in low risk cardiovascular and cerebrovascular patients.
Key words. Turp, aspirin, haemorrhage

Authors: 
Mazhar Khan
Ayesha Inam
Siddique Ahmad
Ravale Tashfeen
Farrukh Ozair
Sadia Muhammad
Journal Issue: 

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