EFFICACY OF BETAMETHASONE DIPROPIONATE VERSUS CALCIPOTRIOL IN TREATMENT OF MILD TO MODERATE CHRONIC PLAQUE PSORIASIS

ABSTRACT
Objectives of study: To compare the efficacy of betamethasone dipropionate with calcipotriol in treatment of mild to
moderate chronic plaque psoriasis.
Methodology: A total of 112 patients were enrolled in our study. These patients were randomly allocated into two
groups A and B by lottery method. Betamethasone dipropionate was given to group A, while Calcipotriol was given
to group B. Response to treatment was assessed on the basis of 50percent reduction in PASI score after 4 weeks of
topical treatment.
Results: In group A the Betamethasosne was efficient in 44 patients (78.57%), while it was not efficient in 12 patients
(21.43%). In group B the Calcipotriol was efficient in 41 patients (73.21%). while it was not efficient in 15(26.79%). The
P value was 0.659 (P>0.05) which is statistically not significant.
Conclusion: Both betamethasone dipropionate and calcipotriol are effective in mild to moderate chronic plaque Psoriasis.
Key Words: Efficacy, Betametasone dipropionate, calcipotriol, chronic plaque psoriasis.