ENDOSCOPIC ENDONASAL TRANSPHENOIDAL APPROACH FOR REPAIR OF CEREBEROSPINAL FLUID RHINORRHEA

ABSTRACT Objective: To know the surgical outcome of endoscopic endonasal transphenoidal approach for repair of cereberospinal fluid rhinorrhea. Material and methods: This prospective study was carried in neurosurgery department Lady Reading, hospital, Peshawar from 1st January 2016 to 30th January 2018. Approval was taken from the ethical committee of MTI, lady reading hospital, Peshawar. After fulfilling inclusion and exclusion criteria the endoscopic endonasal transphenoidal procedure was done. The patient demographics, cause of leakage, duration of leakage, type of leak, symptoms, relevant investigations, site and size of leak, outcome and complications were documented in a pre-designed proforma. The data was entered and analyzed through SPSS Version 22. Results: Total number of patients was 16. Nine (56.25%) patients were males and 7 (43.75%) females. Mean age was 41.06±14.06 years. Cribriform plate (43.75%) was the commonest site of leak. Size of defect ranged from 0.5cm to 2.5cm. Mean size of defect was 1.56cm. One (6.25%) patient had recurrent leak after initial surgery, two (12.5%) patients had meningitis, one (6.25%) patient had pneumocephalus, one (6.25%) patient had nasal bleed and one (6.25%) patient had. Hospital stay ranged from 5 to 8 days. Overall success rate of our procedure on first surgery was 93.75%. Whereas keeping complications in mind, success rate was 68.75%. After addressing the complications and rectifying the recurrent case, the overall success was 100% on last follow up. Conclusion: Endoscopic endonasal transphenoidal approach is a safe and effective procedure for repair of cerebero