TO EVALUATE THE FREQUENCY OF ERECTILE DYSFUNCTION AND RETROGRADE EJACULATION IN PATIENTS, AFTER TWO MONTHS USE OF DUTASTERIDE AND TAMSULOCIN COMBINATIONIN TREATMENT OF BENIGN PROSTATIC HYPERPLASIA

ABSTRACT
Objective: To determine the frequency of erectile dysfunction and retrograde ejaculation, after two months treatment
with dutasteride and tamsulocin among patients with benign prostatic hyperplasia.
Materials and Methods: This study was conducted at Institute of Kidney Diseases, Hayatabad Medical Complex,
Peshawar.Study design was Observational study and the duration of the study was 6 months in which a total of 205
patients were observed with erectile dysfunction10 (7%) and retrograde ejaculation after two months use of dutasteride
and tamsulocin combination in treatment of benign prostatic hyperplasia, 95% confidence interval and 3.5 % margin
of error; using WHO software for sample size calculation. More over consecutive non-probability sampling technique
was used for sample collection.
Results: In this study mean age was 60 years with SD ± 2.16. Baseline IIEF score for all patients was ≥ 22. But after 2
months follow up 17% patients had IIEF score < 22 and 83% patients had IIEF score ≥ 22. Our resultshows that 17%
patients had erectile dysfunction while 37% patients had retrograde ejaculation.
Conlcusion: The combination therapy of dutasteride and tamsulocin has significant effect on patient’s sexual health
for which they need an additional medicine in terms of PDE5 inhibitorsthat imposes extra finances on patient’s pocket.
Key Words: Erectile dysfunction, retrograde ejaculation, dutasteride and tamsulocin, benign prostatic hyperpl