FREQUENCY OF CARCINOMA PROSTATE IN TRANS URETHRAL RESECTION OF PROSTATE SPECIMENS IN PATIENTS WITH CLINICALLY BENIGN PROSTATIC HYPERPLASIA WITH PROSTATE SPECIFIC ANTIGEN LESS THAN 4NG/ML

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Abstract

Back ground/Objectives: To determine the frequency of Carcinoma Prostate in patients with PSA less than 4ng/ml.
Material and methods: This Descriptive cross sectional study was conducted in Surgery Department of Hayatabad
Medical Complex Peshawar and Urology Department of Institute of Kidney Diseases Hayatabad Peshawar from 1st
January 2012 to 31st December 2014. A total of 139 patients above 50 years of age presenting with lower urinary tract
symptoms and enlarged prostate on digital rectal examination were included through non probability consecutive
sampling.
Results: A total of 139 patients with clinically benign prostatic hyperplasia with Prostate specific antigen less than 4ng/
ml were observed, in which 71 (51.08%) patients had prostate specific antigen (PSA) level less than or equal to 2 and
68 (48.92%) patients had more than 2. In 10 (14.7%) out of 68 patients having PSA more than 2 were having Carcinoma
prostate while 58 (85.3%) were non Carcinoma prostate and 7 (10%) patients having PSA less than or equal to 2
were Carcinoma prostate while 64 (90%) were non Carcinoma prostate. The results are statistically insignificant with
a P-value of 0.281.
Conclusion: The incidence of carcinoma prostate among patients with clinically benign prostatic hyperplasia with
Prostate Specific antigen less than 4ng/ml is statistically insignificant but quite high, therefore every TURP specimen
should be sent for histopathology even with normal PSA.
Keywords: Benign prostatic hyperplasia, Carcinoma Prostate, Trans Urethral Resection of Prostate (TURP), Prostate

 

 

 

Authors: 
Irfan Ul Islam Nasir1
Qaisar Iqbal2
Muhammad Iftikhar3
Jamshed Alam4
Imtiaz Ahmed Khattak5
Zafar Iqbal6

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