FREQUENCY OF HEPATORENAL SYNDROME IN PATIENTS WITH LIVER CIRRHOSIS

ABSTRACT
Objective: To determine the frequency of hepatorenal syndrome in patients with liver cirrhosis.
Design: A cross-sectional study.
Place and Duration of Study: From April 2012 to December 2012 at Department of Medicine, Govt: Lady Reading
Hospital Peshawar.
Patients and Methods: A total of 196 patients admitted to the Medical unit, Govt: Lady Reading Hospital Peshawar,
were included in this study after fulfilling the inclusion criteria. All the patients were diagnosed as having liver cirrhosis.
Renal dysfunction was identified in these patients and these patients were worked up for the presence of hepatorenal
syndrome.
Results: Out of one hundred and ninety six (196) patients, 105 (53.6%) were males and 91 (46.4%) were females.
Thirty nine (39) patients were diagnosed as having hepatorenal syndrome based on the diagnostic criteria. Out of 39
patients, 22 (56.4%) were females and 17(43.6%) were males. Mean age of patients having hepatorenal syndrome was
55.64 years. The frequency of hepatorenal syndrome was 19.9% in patients with liver cirrhosis.
Conclusion: Hepatorenal syndrome is a common complication of cirrhosis liver. Data collected through this study
showed that hepatorenal syndrome is a major cause of renal impairment in patients with liver cirrhosis.
Key words: Hepatorenal syndrome, Cirrhosis liver