FREQUENCY OF PANCYTOPENIA IN PATIENTS WITH MEGALOBLASTIC ANAEMIA. A STUDY OF 149 ADMITTED PATIENTS IN A TERTIARY CARE HOSPITAL.

Objectives: To determine the frequency of pancytopenia in patients with megaloblastic anaemia.
Material And Methods: This study was conducted at Medical Units, Khyber Teaching Hospital, Peshawar from January
2013 to January 2014. Study Design was cross-sectional (descriptive). More over non probability, consecutive sampling
technique was used and the sample size was determined by WHO formula. Total 149 patients with megaloblastic
anemia were screened for pancytopenia.
Results: In this study mean age was computed as 33 years with standard deviation as ± 15.84. Fifty eight percent
patients were males and 42% patients were females. Male to female ratio was 2:1. More over pancytopenia was found
in 70% patients with megaloblastic anemia and was absent in 30% patients.
Conclusion: Megaloblastic aneamia and Pancytopenia are common problems in clinical and haematological practice.
A vast majority of diseases may present with pancytopenia so it is of utmost importance to know the common causes
of pancytopnia to reduce the morbidity and mortality.
Key Words: Pancytopenia, Meglaboblastic anemia, Bone marrow aspiration, Aplastic anemia