PATTERN OF ISOLATIONS AND SENSITIVITY IN SURGICAL PATIENTS PRESENTED TO KHYBER TEACHING HOSPITAL

ABSTRACT
Objectives: To determine sensitivity pattern of surgical sites infection.
Material and Methods: Pus from 204 patients was sent for culture sensitivity by swab or in a sterile container from the
site of surgical infection. The study was conducted in surgical C ward KTH Peshawar from June 2011 to December 2012.
Culture sensitivity was performed by standard disc diffusion method by qualified pathologist. This was a descriptive
cross-sectional study. Data was analysed using SPSS 17.
Results: In clean cases, Staphylococcus Aureus was isolated in 96.1% of cases. E-Coli were the leading cause of
infection in clean contaminated cases. In contaminated cases, citrobacter was isolated in 49% of the cases Sensitivity
to imepenem, meronem, piperacillin/tazobactum, Co-Amoclave and Cefuroxime was observed in decreasing order
in clean cases. In clean contaminated cases Amikacin, piperacillin and meronen were equally sensitive (greater than
30% sensitivity), yet imipenem showed the greatest sensitivity (greater than 40%). Sensitivity to Co- Amoxiclave was
less than that found in clean cases (32% versus 23%). Sensitivity of the organisms was almost the same in both the
contaminated and dirty cases.
Conclusion: Anticipation of expected organisms and their sensitivity to the drugs before the availability of culture
sensitivity should be logic and evidence based.
Keywords: surgical site infections, wound infections, antibiotic sensitivity