SERO-PREVALENCE OF HEPATITIS B AND C VIRUS IN PATIENTS WITH HEPATOCELLULAR CARCINOMA

×

Error message

Deprecated function: The each() function is deprecated. This message will be suppressed on further calls in _menu_load_objects() (line 579 of /home/kjmscomp/public_html/old/includes/menu.inc).

Abstract

Objective: To know about the sero-prevalence of hepatitis B and C virus in patients with hepatocellular carcinoma (HCC).
Study design: Descriptive observational Study.
Place and Duration of Study: This study was conducted in Medical units of Naseer Teaching Hospital and Khyber
Teaching Hospital, Peshawar from June 2012 to June 2013.
Materials and Methods: A total of 100 diagnosed cases of hepatocellular carcinoma were studied. A detailed history
and clinical examination was performed in each case. Serological assessment for hepatitis B, hepatitis C and delta
virus was carried out through ELISA. Liver function tests (LFTs) were performed in all patients.
Results: A total of 100 diagnosed cases of HCC were enrolled comprising 62 male and 28 female. Mean age was
55.4± 12.35 years with age range of 20 to 75 years. HCV infection was found in 52%, HBV infection in 28%, both HCV
and HBV infection in 10%, alcoholism in 6%. No cause found in 4% of patients. 48% of patients presented in Class A,
30% in Class B and 22% in Class C according to Child-Pugh Classification.
Conclusion: Chronic Hepatitis B and Hepatitis C are the most common causes of cirrhosis and HCC.
Keywords: Sero-Prevalence, Hepatitis B virus, Hepatitis C virus, Hepatocellular Carcinoma

Authors: 
superShafaq userNaz
Muhammad Arshad
Jamal ud-din

PDF