VAGINAL MISOPROSTOL FOR INDUCTION OF LABOUR

ABSTRACT
Objective: To determine the safety and efficacy of vaginal misoprostol for induction of labour at term by determining
the optimal dose with respect to ease of administration and induction to delivery time interval.
Study Design:
Observational study.
Place and duration of study: Gynecology/Obstetrics department Hayatabad Medical Complex, Peshawar from May
2015- April 2016.
Methodology: Women with gestational age more than 36 weeks and cephalic presentation, with an indication for
induction of labour were induced. Vaginal misoprostol 50-400 µgm was given and divided doses at 6 hours interval up
to maximum of 3 doses. Fetomaternal outcome and induction to delivery time interval noted.
Result: In this one year study, 127 women were enrolled. The main indication for labor induction were post date preg-
nancy (37.79%) and PROM (22.83%). The majority (81,1%) of  women went into labour but (13.6%) have failed induction.
The majority (82.52%) of mother delivered vaginallyin the first 15 hours.The mean induction to delivery interval was
12 hours. Caesarean sections were performed on 24 (18.89%) women. All the babies were delivered with good Apgar
score. Maternal hyper stimulation was noted in none of women.
Conclusion: Vaginal misoprostol was found safe easy and effective agent for labour induction.
Keywords: Misoprostol, Induction of labour