FREQUENCY OF COMMON RISK FACTORS OF RECURRENT DIABETIC KETOACIDOSIS AMONG CHILDREN

Abstract

OBJECTIVE: To determine the frequency of common risk factors leading to recurrent diabetic ketoacidosis among children.

MATERIAL AND METHODS: This study was conducted at the department of pediatric medicine Hayatabad Medical Complex, Peshawar from March 2017 to September 2018. In this study a total of 290 patients were observed. All patients were thoroughly checked for the presence of recurrent DKA. History of infections like RTI, diarrhea, UTI and typhoid in the last one week and information obtained about the timing, dose and frequency of insulin therapy. Sample of blood and urine sent to hospital laboratory for various risk factor identifications including typhidotIgM and IgG status, urine R/E and culture for confirmation of current infection. All the laboratory investigations were done from hospital laboratory under the supervision of an expert pathologist.

 RESULTS: The study showed that mean age was 9 years with standard deviation ± 4.761. Sixty five percent patients were male while 35% patients were female. UTI was the most common found risk factor constituting 48% of cases followed by typhoid detected in 38% children. Acute diarrhea was found in 35% children while RTI was found in 33% children and inadequate insulin was found in 24% children.

 CONCLUSION:  Infections are one of the leading causes for the exacerbation of recurrent diabetic ketoacidosis among children with urinary tract infection as the most common one