CLOVES SYNDROME: A CASE REPORT

Abstract

CLOVES syndrome is an extremely rare PIK3CA-related overgrowth syndrome encompassing, but not restricted to, congenital lipomatous overgrowths (CLO), vascular malformations (V), epidermal naevi (E) and spinal deformities (S). The syndrome can have features overlapping with other overgrowth syndromes resulting in a challenging diagnosis and frequent misdiagnosis. To the best of our knowledge, reports on the syndrome are lacking from Pakistan. We report a rare case of CLOVES syndrome in a previously misdiagnosed 2-year-old male child from Khyber Pakhtunkhwa, Pakistan.