FREQUENCY OF DIABETES MELLITUS IN PATIENTS WITH IMMUNO-BULLOUS DISORDERS

Abstract

Objectives: To determine the frequency of type 2 diabetes mellitus in patients with immunobullous disorders

Methods and patients: The study was conducted in the dermatology department, Khyber Teaching Hospital, Peshawar from July 30, 2021 to January 30, 2022. After taking full history and physical examination, patients with IBD aged 20 to 80 years were screened for type 2 diabetes mellitus, defined as a random blood glucose level of over 200 mg/dl.  The test was done using Micro Lab 300 of Vital Scientific using Glucose; GOD-PAP of Dialab. All data were analyzed by SPSS 22. Post stratification Chi-square test was used to determine the association of duration of IBDs and use of systemic steroids with the presence of diabetes mellitus.  

Results: Among these 152 patients, 59.2% were female. The mean age was 47.77 years ± 14.30 SD and duration of the disease was 3.12 years ± 1.76 SD. The frequency of diabetes mellitus was 23.7%. Diabetes mellitus was significantly more prevalent in patients with disease duration of more than three years (46.7% versus 8.7%, p = 0.001) and in those with a history of use of systemic steroids for the IBDs (39% versus 10%, p = 0.001).

Conclusion: The frequency of type 2 diabetes mellitus was 23.7% among patients with IBDs. Earlier detection of type 2 diabetes mellitus can prevent the associated complication of the disease including the morbidity and mortality.