EFFECTIVENESS OF OF ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY FOR TREATMENT OF OBSTRUCTIVE JAUNDICE

Abstract

Background: Endoscopic retrograde cholangiopancreatography is one of leading procedures for diagnosis and management of obstructive jaundice.

Objective: To assess the effectiveness of endoscopic retrograde cholangiopancreatography for biochemical and symptomatic improvement in patients of obstructive jaundice

Results: The mean age of the patient was 51 years with a minimum of 30 and maximum of 79 years. There was equal male to female ratio.46% of patients had CBD stones ,43% had strictures in CBD,8.4% had carcinoma pancreas and 2.6% had periampullary growth .46% patients  underwent sphincterotomy with balloon extraction while 54% had stent placement for stones evacuation and drainage of bile flow  74% of the patients had significant improvement of clinical symptoms in 7 days while 26% had improvement in 3 days .Post ERCP pancreatitis was 2% of cases .The mean ALT and AST before intervention were 124 and 123 units/L respectively .The mean ALP and bilirubin were 602 and 4.6 units/L respectively .The mean ALT,AST,bilirubin and ALP after the intervention were 73,74,410 and 2.6 units/L respectively. Significant improvement was seen in the liver function tests, clinical symptoms as reflected by a p value of less than 0.05

Conclusion: In conclusion ERCP is an excellent therapeutic procedure for the management of obstructive jaundice.